T Cell Abnormalities in Mixed Connective Tissue Disease Complicated with Klinefelter's Syndrome.
نویسندگان
چکیده
منابع مشابه
B cell Therapy to Treat an Axonal Neuropathy in Mixed Connective Tissue Disease
The B cell is a vital contributor to humoral immunity. The B cell-specific antigen CD20 is expressed during B cell development, starting at the pre-B cell level and persists through B cell differentiation, but is lost during terminal differentiation to plasma cells. Rituximab is a monoclonal antibody that destroys both normal and malignant B cells that have CD20 on their surfaces and is ther...
متن کاملMixed Connective Tissue Disease Complicated by Retinal Microvasculopathy and Its Relationship with Fragile-X Syndrome
Purpose: To report an unusual case of retinal microvasculopathy secondary to mixed connective tissue disease (MCTD) on a background history of fragile-X syndrome (FXS). Methods: Case report and literature review. Results: A cotton wool spot was discovered in a 29-year-old female who presented with an ischaemic digit secondary to Raynaud’s phenomenon. She also has a background history of MCTD an...
متن کاملMinimal-change nephrotic syndrome associated with mixed connective-tissue disease.
Sir, Mixed connective-tissue disease (MCTD) is a rheumato-logical disorder which has combined features of systemic lupus erythematosus, systemic sclerosis (SSc), polymyositisu dermatomyositis, and rheumatoid arthritis (RA) with anti-bodies to U 1 small nuclear ribonucleoprotein (U 1 snRNP). Although renal involvement was considered to be rare in the initial description w1x, several studies demo...
متن کامل[Mixed connective tissue disease].
Mixed connective tissue disease deserves to be a distinct disease entity due to the persistent citation of this disease in the literature since the original description by Sharp in 1972, in spite of the presence of several criticisms against the independency of this disease. The characteristic features of mixed connective tissue disease are: 1) the presence of anti-U1snRNP antibody with high ti...
متن کاملSjögren's syndrome: An underdiagnosed condition in mixed connective tissue disease
OBJECTIVE To determine the prevalence of sicca symptoms, dry eye, and secondary Sjögren's syndrome and to evaluate the severity of dry eye in patients with mixed connective tissue disease. METHODS In total, 44 consecutive patients with mixed connective tissue disease (Kasukawa's criteria) and 41 healthy controls underwent Schirmer's test, a tear film breakup time test, and ocular surface stai...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 1994
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.33.714